Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep1022 | Hot topics (including COVID-19) | ECE2020

miRNAs regulating BDNF and BDNFas in adipose tissue: Potential link between obesity and mood disorders

Lhamyani Said , Clemente Mercedes , Gentile Adriana , Chacón Pedro , Javier Pavón Francisco , José Tinahones Francisco , Olveira Gabriel , El Bekay Rajaa

Background and aim: Obesity (Ob) is tightly associated with metabolic diseases such as type 2 diabetes (DT2) andinsulin resistance (IR). Furthermore, obesity has been identified as one of the primary causes of mood disorders (MDs) including depression. Several studies have demonstrated the link between Ob, adiposity, neuroinflammation and MDs. The Brain-Derived Neurotrophic Factor (BDNF) and its regulator, the non-coding RNA BDNF antisense RNA (BDNFas), play an import...